Cell Line Lysates
ABclonal Technology MSH6 Rabbit pAb
This gene encodes a member of the DNA mismatch repair MutS family. In E. coli, the MutS protein helps in the recognition of mismatched nucleotides prior to their repair. A highly conserved region of approximately 150 aa, called the Walker-A adenine nucleotide binding motif, exists in MutS homologs. The encoded protein heterodimerizes with MSH2 to form a mismatch recognition complex that functions as a bidirectional molecular switch that exchanges ADP and ATP as DNA mismatches are bound and dissociated. Mutations in this gene may be associated with hereditary nonpolyposis colon cancer, colorectal cancer, and endometrial cancer. Transcripts variants encoding different isoforms have been described.
Sino Biological Recombinant Mouse S100A4 Protein (His & AVI Tag), Avi-tag Biotinylated, HPLC-verified 100 µg
A DNA sequence encoding the Mouse S100A4 (NP_035441.1) (Met1-Lys101) was expressed with a N-terminal polyhistidine tag followed by an AVI tag.The expressed protein was biotinylated in vivo by the Biotin-Protein ligase (BirA enzyme) which is co-expressed.
Abcam Human BCAR3 (NSP2) knockout HeLa cell lysate.
Human BCAR3 (NSP2) knockout HeLa cell lysate.
The product is subject to the following: Abcam Restricted Use Statement
Cayman Chemical EnopeptIn A 2.5mg
A depsipeptide antibiotic that contains two unusual amino acids (N-methylalanine and 4-methylproline) and features a pentaenone side chain; effective against Gram-positive bacteria, including methicillin-resistant S. aureus (MIC = 25 UG/ml), and Gram-negative bacteria, including mutant forms of E. coli and P. aeruginosa (MICs = 200 UG/ml) yet does not inhibit fungi
Abcam Human LAMP3 knockout HeLa cell lysate.
Human LAMP3 knockout HeLa cell lysate.
The product is subject to the following: Abcam Restricted Use Statement
Cayman Chemical QuInaldopeptIn 2.5mg
A quinomycin antibiotic; active against a variety of bacteria, including S. pyogenes, S. aureus, C. perfringens, S. faecalis, E. coli, and K. pneumoniae (MICs = 0.2, 0.4, 0.8, 1.6, 3.1, and 6.3 UG/ml, respectively); cytotoxic to B16/F10 and Moser cells (IC50s = 0.0008 and 0.04 UG/ml, respectively); increases survival in a P388 leukemia mouse model; binds to and intercalates into DNA (Kd = 32 nM)
Cayman Chemical SaccharocarcIn A 2.5mg
An antibiotic; active against M. luteus, S. aureus, E. coli, P. aeruginosa, and C. albicans in a disc assay; inhibits C. trachomatis infection in McCoy cells
Cayman Chemical Aszonapyron A 2.5mg
A meroditerpene fungal metabolite with diverse biological activities; inhibits the growth of MCF-7, NCI H460, and A375-C5 cancer cells (GI50s = 13.6, 11.6, and 10.2 μM, respectively); active against multidrug-resistant isolates of S. aureus, E. faecalis, and E. faecium (MICs = 8, 16, and 16 μg/ml, respectively) and inhibits S. aureus biofilm formation; active against P. falciparum in vitro (IC50 = 1.34 μg/ml)
ABclonal Technology ATF6 Rabbit pAb
This gene encodes a transcription factor that activates target genes for the unfolded protein response (UPR) during endoplasmic reticulum (ER) stress. Although it is a transcription factor, this protein is unusual in that it is synthesized as a transmembrane protein that is embedded in the ER. It functions as an ER stress sensor/transducer, and following ER stress-induced proteolysis, it functions as a nuclear transcription factor via a cis-acting ER stress response element (ERSE) that is present in the promoters of genes encoding ER chaperones. This protein has been identified as a survival factor for quiescent but not proliferative squamous carcinoma cells. There have been conflicting reports about the association of polymorphisms in this gene with diabetes in different populations, but another polymorphism has been associated with increased plasma cholesterol levels. This gene is also thought to be a potential therapeutic target for cystic fibrosis.
Genscript Corporation NRG1 Beta 1 hFc ChimeraBiotin
euregulin-1 (NRG-1) is a ligand of the epidermal growth factor receptor (erbB) and its interaction involves activation of the glutamatergic N-methyl-Daspartate receptor which increases the expression of the 2 subunit of the - aminobutyric acid receptor and subunits of the nicotinic acetylcholine receptor
Abcam Human SLC39A8 (BIGM103/ZIP8) knockout HeLa cell lysate.
Human SLC39A8 (BIGM103/ZIP8) knockout HeLa cell lysate.
The product is subject to the following: Abcam Restricted Use Statement
Eurofins Discoverx InCELL Hunter™ Human Bcl2-Bax Target Engagement Cell-Based Assay Kit (U2OS)
The InCELL Hunter™ Human BCL2-BAX Stable Cell Line Target Engagement Assay (U2OS) contains a stable clonal cell line used to measure protein binding via compound-induced binding partner disruption and degradation. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Biochain Institute Inc Total Protein - Arrhythmia, infarct: Heart, 1 mg/PK
Tissue total protein is prepared from whole tissue homogenates. It presents a consistent pattern on SDS-PAGE analysis. The total protein is stored in a buffer with protease inhibitor cocktail, and provided at a concentration of 5 mg/ml.
Abcam Human TIMM17B knockout HEK-293T cell lysate.
Human TIMM17B knockout HEK-293T cell lysate.
The product is subject to the following: Abcam Restricted Use Statement
ABclonal Technology CCR7 Rabbit pAb
The protein encoded by this gene is a member of the G protein-coupled receptor family. This receptor was identified as a gene induced by the Epstein-Barr virus (EBV), and is thought to be a mediator of EBV effects on B lymphocytes. This receptor is expressed in various lymphoid tissues and activates B and T lymphocytes. It has been shown to control the migration of memory T cells to inflamed tissues, as well as stimulate dendritic cell maturation. The chemokine (C-C motif) ligand 19 (CCL19/ECL) has been reported to be a specific ligand of this receptor. Signals mediated by this receptor regulate T cell homeostasis in lymph nodes, and may also function in the activation and polarization of T cells, and in chronic inflammation pathogenesis. Alternative splicing of this gene results in multiple transcript variants.